围绕光治疗开展相关工作，包括光功能药物的设计与合成及多模式协同治疗等。

 

访问学者：2017 年3 月-2018 年3 月，Nanyang Technological University

博士：2012 年9 月-2017 年12 月，南京工业大学 

学士：2008 年9 月-2012 年6 月，南京工业大学                     

 

2021 年1 月-至今，杭州医学院附属浙江省人民医院，副研究员

2018 年1 月-2020 年12 月，南京大学医学院附属口腔医院，助理研究员                    

 

国家自然科学基金青年项目

浙江省医坛新秀

浙江省医药卫生青年创新项目

浙江省医药卫生科技计划一般项目

浙江省中医药传承创新人才支持计划

杭州医学院基本科研业务费一般科研基金项目

浙江省人民医院科研启动基金

 

近期发表论文：

[1] D. Chen, T. Zhang, A. Jiao, X. Mou, X. Dong,Y. Cai*, Molecular endoperoxides for optical imaging and photodynamic therapy, Coordination Chemistry Reviews 523 (2025). 

[2] Y. Xu, J. Jiang, X. Lv, H. Li, D. Yang, W. Wang, Y. Hu, L. Liu, X. Dong, Y. Cai*, Environment-triggered nanoagent with programmed gas release performance for accelerating diabetic infected wound healing, Chemical Engineering Journal 479 (2024).

[3] L. Zhao, Y. Chen, Q. Wei, X. Lv, Y. Cui, W. Wang, X. Mou, X. Song, X. Dong, Y. Cai*, H2O2 self-supplied CuFeOx nanosystem as fenton-like reaction agents for endogenous/exogenous responsive synergetic antibacterial therapy, Chemical Engineering Journal 492 (2024). 

[4] L. Liu, Y. Pan, L. Ye, C. Liang, X. Mou, X. Dong, Y. Cai*, Optical functional nanomaterials for cancer photoimmunotherapy, Coordination Chemistry Reviews 517 (2024).

[5] X. Zhao, F. Yin, Y. Huang, L. Fu, Y. Ma, L. Ye, W. Fan, W. Gao, Y. Cai*, X. Mou, Oral administration of grape-derived nanovesicles for protection against LPS/D-GalN-induced acute liver failure, International Journal of Pharmaceutics 652 (2024). 

[6] D. Wu, X. Chen, S. Yao, Y. He, G. Chen, X. Hu, Y. Chen, Z. Lv, J. Yu, K. Jin, Y. Cai, X. Mou, Platelet Membrane Coated Cu9S8-SNAP for Targeting NIR-II Mild Photothermal Enhanced Chemodynamic/Gas Therapy of Triple-Negative Breast Cancer, Small 20(35) (2024). 

[7] Z. Wei, W. Si, M. Huang, M. Lu, W. Wang, C. Liang, X. Dong, Y. Cai*, Autophagy Blockage Enhancing Photothermal and Chemodynamic Synergistic Therapy Based on HCQ/CuS Nanoplatform, Advanced Healthcare Materials (2024).

[8] W. Fan, Y. He, P. Hu, L. Liu, X. Yang, T. Ge, K. Jin, X. Mou, Y. Cai*, A novel acceptor-donor-acceptor structured molecule-based nanosystem for tumor mild photothermal therapy, Journal of Colloid and Interface Science 670 (2024) 762-773.

[9] S. Yao, D. Wu, X. Hu, Y. Chen, W. Fan, X. Mou, Y. Cai*, X. Yang, Platelet membrane-coated bio-nanoparticles of indocyanine green/elamipretide for NIR diagnosis and antioxidant therapy in acute kidney injury, Acta Biomaterialia 173 (2024) 482-494. 

[10] L. Liu, Y. Chen, L. Ye, L. Yu, Y. Kang, X. Mou, Y. Cai*, NIR-II Absorbed Dithienopyrrole-Benzobisthiadiazole Based Nanosystems for Autophagy Inhibition and Calcium Overload Enhanced Photothermal Therapy, Small 20(37) (2024).

[11] Y. Chen, L. Liu, L. Yu, Y. Kang, S. Yao, D. Wu, J. Xu, X. Mou, Y. Cai*, Succinct NIR-II absorbed croconic acid-julolidine molecule uniting Fe (III)-quercetin complex for efficient mild photothermal therapy of oropharyngeal carcinoma, Chemical Engineering Journal 488 (2024). 

[12] J. Huang, L. Ji, J. Si, X. Yang, Y. Luo, X. Zheng, L. Ye, Y. Li, S. Wang, T. Ge, X. Tong, Y. Cai*, X. Mou, Platelet membrane-coated oncolytic vaccinia virus with indocyanine green for the second near-infrared imaging guided multi-modal therapy of colorectal cancer, Journal of Colloid and Interface Science 671 (2024) 216-231. 

[13] X. Hu, D. Wu, S. Yao, G. Chen, P. Li, Y. Chen, W. Gong, W. Fan, X. Chen, X. Mou, Y. Cai*, X. Yang, Platelet membrane coated Cu9S8-SNAP for NIR-II photoacoustic imaging guided NO repairing acute kidney injury, Chemical Engineering Journal 495 (2024).

[14] C. Tang, Y. Pan, Z. Wei, L. Liu, J. Xu, W. Han, Y. Cai*, Side-chain engineering of organic photothermal agents for boosting further red-shifted absorption and higher photothermal therapeutic effect, Colloids and Surfaces B-Biointerfaces 233 (2024). 

[15] L. Ji, J. Huang, L. Yu, H. Jin, X. Hu, Y. Sun, F. Yin, Y. Cai*, Recent advances in nanoagents delivery system-based phototherapy for osteosarcoma treatment, International Journal of Pharmaceutics 665 (2024).

[16] Y. Cai*, Z. Lv, X. Chen, K. Jin, X. Mou, Recent advances in biomaterials based near-infrared mild photothermal therapy for biomedical application: A review, International Journal of Biological Macromolecules 278 (2024). 

[17] G. Chen, F. Yang, D. Wu, J. Yang, X. Hu, L. Liu, Y. Kang, W. Fan, X. Mou, Y. Cai*, C. Hou, Naphthalene Diimide-Based Polycyclic Conjugated Molecule Composite CoFe2O4 Nanohybrids for Photoacoustic Imaging-Mediated Photo-/Sonic Therapy, Advanced Healthcare Materials (2024). 

[18] J. Zhu, C. Wang, Q. Wei, Y. Su, X. Qu, W. Wang, X. Song, X. Dong, Y. Cai*, PtMo-Au Metalloenzymes Regulated Tumor Microenvironment for Enhanced Sonodynamic/Chemodynamic/Starvation Synergistic Therapy, Small 19(45) (2023). 

[19] X. Zhao, F. Yin, L. Fu, Y. Ma, L. Ye, Y. Huang, W. Fan, W. Gao, Y. Cai*, X. Mou, Garlic-derived exosome-like nanovesicles as a hepatoprotective agent alleviating acute liver failure by inhibiting CCR2/CCR5 signaling and inflammation, Biomaterials Advances 154 (2023). 

[20] X. Zhao, L. Fu, H. Zou, Y. He, Y. Pan, L. Ye, Y. Huang, W. Fan, J. Zhang, Y. Ma, J. Chen, M. Zhu, C. Zhang, Y. Cai*, X. Mou, Optogenetic engineered umbilical cord MSC-derived exosomes for remodeling of the immune microenvironment in diabetic wounds and the promotion of tissue repair, Journal of Nanobiotechnology 21(1) (2023). 

[21] X. Zhang, Z. Cao, C. Song, Z. Wei, M. Zhou, S. Chen, J. Ran, H. Zhang, H. Zou, S. Han, Y. Cai*, W. Han, Cholesterol Metabolism Modulation Nanoplatform Improves Photo-Immunotherapeutic Effect in Oral Squamous Cell Carcinoma, Advanced Healthcare Materials 12(22) (2023).

[22] W. Wang, G. Zhang, Y. Wang, J. Ran, L. Chen, Z. Wei, H. Zou, Y. Cai*, W. Han, An injectable and thermosensitive hydrogel with nano-aided NIR-II phototherapeutic and chemical effects for periodontal antibacteria and bone regeneration, Journal of Nanobiotechnology 21(1) (2023).

[23] W. Wang, J. Yu, Y. Lin, M. Li, Y. Pan, Y. He, L. Liu, X. Meng, Z. Lv, K. Jin, S. Che, X. Mou, Y. Cai*, NIR absorptive croconic acid/quercetin/CaO2 nanoplatform for tumor calcium overload therapy combined mild photothermal therapy, Biomaterials Advances 149 (2023).

[24] C. Song, X. Zhang, Z. Cao, Z. Wei, M. Zhou, Y. Wang, S. Han, Y. Cai*, W. Han, Regulating tumor cholesterol microenvironment to enhance photoimmunotherapy in oral squamous cell carcinoma, Chemical Engineering Journal 462 (2023). 

[25] J. Ran, T. Liu, C. Song, Z. Wei, C. Tang, Z. Cao, H. Zou, X. Zhang, Y. Cai*, W. Han, Rhythm Mild-Temperature Photothermal Therapy Enhancing Immunogenic Cell Death Response in Oral Squamous Cell Carcinoma, Advanced Healthcare Materials 12(6) (2023).

[26] Y. Pan, L. Liu, X. Mou, Y. Cai*, Nanomedicine Strategies in Conquering and Utilizing the Cancer Hypoxia Environment, ACS Nano 17(21) (2023) 20875-20924.

[27] Y. Pan, L. Liu, Y. He, L. Ye, X. Zhao, Z. Hu, X. Mou, Y. Cai*, NIR diagnostic imaging of triple-negative breast cancer and its lymph node metastasis for high-efficiency hypoxia-activated multimodal therapy, Journal of Nanobiotechnology 21(1) (2023).

[28] L. Liu, Y. Pan, L. Ye, T. Zhang, Y. Chen, C. Liang, D. Chen, X. Mou, X. Dong, Y. Cai*, Space and Bond Synergistic Conjugation Controlling Multiple-Aniline NIR-II Absorption for Photoacoustic Imaging Guided Photothermal Therapy, Advanced Healthcare Materials 12(27) (2023). 

[29] Y. He, Y. Pan, X. Zhao, L. Ye, L. Liu, W. Wang, M. Li, D. Chen, Y. Cai*, X. Mou, Camouflaging multifunctional nanoparticles with bacterial outer membrane for augmented chemodynamic/photothermal/starvation/chemo multimodal synergistic therapy of orthotopic glioblastoma, Chemical Engineering Journal 471 (2023). 

[30] Y. Cai, Y. Pan, L. Liu, T. Zhang, C. Liang, X. Mou, X. Ye, W. Wang, X. Dong, Succinct croconic acid-based near-infrared functional materials for biomedical applications, Coordination Chemistry Reviews 474 (2023). 

[31] L. An, L. Zheng, Z. Zhao, X. Qu, C. Liang, C. Ou, X. Mou, X. Dong, Y. Cai*, Revisiting molecularly conformation-planarized organic dyes for NIR-II fluorescence imaging, Journal of Materials Chemistry B 11(35) (2023) 8456-8463.