医学博士，主任助理，入选院后备学科带头人、浙江省省级青年人才，以第一或者通讯作者发表SCI论文20余篇，专利6项。因材施教，手把手指导学生开展学术研究，确保学生准时毕业和丰富学术成果，力争每位研究生以第一作者发表SCI论文2篇及以上。带领学生勇攀学术高峰。重教爱教，注重学生综合素质的培养。

 

2008 年9 月-2016 年6 月，华中科技大学，临床医学八年制，医学博士     

 

2022年12 月-至今，杭州医学院附属，浙江省人民医院，副主任医师 

2017年12 月-2022年11月，杭州医学院附属，浙江省人民医院，主治医师

2016 年8 月-2017年12 月，杭州医学院附属，浙江省人民医院，住院医师     

 

1.2025年， 浙江省省级青年人才

2.2023年，浙江省人民医院 后备学科带头人

3.2021年，杭州医学院优秀科研奖   

 

1. 中国抗癌协会肿瘤营养专业委员会中西医结合营养专家协作委员

2. 浙江省数理医学会肿瘤粒子与营养智能诊疗专业委员会委员

3. 浙江省医学会放射肿瘤治疗学分会委员会青年委员

4. 浙江省数理医学会肿瘤支持治疗专业委员会青年委员

5. 浙江省健康服务业促进会放射治疗专业委员会青年委员

6. 甘肃省自然科学基金以及科技厅评审专家    

 

主持国家自然科学基金2项，省自然科学基金1项，医药卫生科技计划1项

1.FBXW11/USP11调控DHX30蛋白质稳定性影响JAK2/STAT3信号通路在肺癌放疗抵抗中的作用及机制研究，国家自然科学基金项目， 2025年-2028年

2.MYST2结合长链非编码RNA-PVT1形成复合体靶向调控H3K14/TIF1/HMG1L2促进非小细胞肺癌放疗抵抗，国家自然科学基金项目，2021年-2023 年

3.FBXW11介导COBL蛋白质泛素化降解激活MAPK/ERK信号通路促进非小细胞肺癌放疗抵抗机制研究，浙江省自然科学基金，2024 年-2026 年     

4.大分割和常规分割放疗模式在肺癌中放射生物学效应差异及联合免疫治疗研究，浙江省医药卫生科技计划，2022年-2024 年

 

 

代表性论文如下（#共同第一作者；* 共同通讯作者，以第一或者通讯作者发表SCI论文20余篇，累计IF＞100）：

1) Jianming Tang^a,b#*, Jing Li^b#, Jiayan Lianc^#, Yumei Huangd^#, Yaqing Zhange^#, Yanwei Lu^f, Guansheng Zhongg, Yaqi Wang^b, Zhitao Zhang^b, Xin Bai^b, Min Fang^f, Luming Wu^h, Haofei Shen^h, Jingyuan Wu^h, Yiqing Wang^h*, Lei Zhangi^*, Haibo Zhang^f*.CDK2-activated TRIM32 phosphorylation and nuclear translocation promotes radioresistance in triple-negative breast cancer. Journal of Advanced Research. 2023 Sep 19. （通讯作者, IF=11.4）

2) Ruiqi Liu^#, Yanwei Lu^#, Jing Li^#, Weiping Yao^#, Jiajun Wu, Xiaoyan Chen Luanluan Huang, Ding Nan, Yitian Zhang, Weijun Chen, Ying Wang, Yongshi Jia, Jianming Tang^*, Xiaodong Liang^*, Haibo Zhang^*. Annexin A2 combined with TTK accelerates esophageal cancer progression via the Akt/mTOR signaling pathway. Cell Death Dis. 2024 Apr 24;15(4):291.（通讯作者,  IF=9.0） 

3)Wang Ying^#, Chen Wanyuan^#, Lian Jiayan^#, Zhang Haibo^#, Yu Bo, Zhang Minjun, Wei Fangqiang, Wu Jianhui, Jiang Jiaxiang, Jia Yongshi, Mo Fan, ZhangShirong, Liang Xiaodong^*, Mou Xiaozhou^*, Tang Jianming^*. The lncRNA PVT1regulates nasopharyngeal carcinoma cell proliferation via activating the KAT2A acetyltransferase and stabilizing HIF-1α.  Cell Death and Differentiation, 2019, 27(2): 695-710. (共同第一作者，IF=12.067)

4) Ruiqi Liu^#, Jiajun W^#, Haiwei Guo, Weiping Yao, Shuang Li, Yanwei Lu, Yongshi Jia, Xiaodong Liang^*, Jianming Tang^*, Haibo Zhang^*. Post-translational modifications of histones: Mechanisms, biological functions, and therapeutic targets. MedComm. 2023 May 20;4(3):e292. （通讯作者, IF=10.7）

5) Xiao Wang^#, Ruiqi Liu^#, Shuang Li, Wenjie Xia, Haiwei Guo, Weiping Yao, Xiaodong Liang, Yanwei Lu^*, Haibo Zhang^*. The roles, molecular interactions, and therapeutic value of CDK16 in human cancers. BIOMEDICINE & PHARMACOTHERAPY. 2023 May 24;164:114929.（通讯作者, IF=7.5）

6) Qiang Li^#, Yiming Jiang^#, Guansheng Zhong, Yanwei Lu, Tao Song, Yigan Zhang, Jianhui Wu, Minjun Zhang, Xiaodong Liang, Liheng Zhou, Jianming Tang^*, Haibo Zhang^*. Long Noncoding RNA DANCR Regulates Cell Proliferation by Stabilizing SOX2 mRNA in Nasopharyngeal Carcinoma. American Journal of Pathology. 2020:S0002-9440(20)30422-3. （通讯作者, IF=5.77）

7) Haiwei Guo^#, Ruiqi Liu^#, Jiajun Wu, Shuang Li, Weiping Yao, Jiajie Xu, Chuanming Zheng, Yanwei Lu, Haibo Zhang^*. SRPX2 promotes cancer cell proliferation and migration of papillary thyroid cancer. CLINICAL AND EXPERIMENTAL MEDICINE. 2023;10.1007/s10238-023-01113-1. （通讯作者, IF=5.057）

8) Ruiqi Liu^#, Xiaodong Liang^#, Haiwei Guo, Shuang Li, Weiping Yao, Chenfang Dong, Jiajun Wu, Yanwei Lu^*, Jianming Tang^*, Haibo Zhang^*. STNM1 in human cancers: role, function and potential therapy sensitizer. Cellular Signalling. 2023 Jun 17;109:110775. （通讯作者, IF=4.94）

9) Qiang Li^#, Xiao Wang^#, Liheng Zhou^#, Mingyun Jiang, Guansheng Zhong, Shuguang Xu, Minjun Zhang, Yigan Zhang, Xiaodong Liang, Lei Zhang^*, Jianming Tang^*, Haibo Zhang^*. A Positive Feedback Loop of Long Noncoding RNA LINC00152 and KLF5 Facilitates Breast Cancer Growth. Frontiers in Oncology. 2021 Mar 26;11:619915.（通讯作者, IF=5.738）

10) Weiping Yao^#, Shuang Li^#, Ruiqi Liu, Liang Gao, Yanwei Lu, Xiaodong Liang^*, Haibo Zhang^*. Long non-coding RNA PVT1: a promising chemotherapy and radiotherapy sensitizer. Frontiers in Oncology. 2022 July 29; 12:959208 （通讯作者, IF=5.738）

11) Wang, Xiao^#; Lu, Yanwei^#; Qin, Zhiquan; Guo, Haiwei; Chen, Wenjuan; Ding, Ting; Tang, Jianming^*; Zhang, Haibo^*; Stereotactic Body Radiotherapy and Conventional Radiotherapy Induce Cytoskeleton Extension and Enlargement of Cell Morphology in Non-Small Cell Lung Cancer. Dose-Response, 2021, 19(4): 0-15593258211064499. （通讯作者, IF=2.623）

12) Haibo Zhang^#, Weiping Yao^#, Minjun Zhang, Yanwei Lu, Jianming Tang, Mingyun Jiang, Xiaozhou Mou, Guangxian You^*, Xiaodong Liang^*. TTK inhibitor promotes radiosensitivity of liver cancer cells through p21. Biochemical and Biophysical Research Communications. 2021 Apr 23;550:84-91.（第一作者, IF=3.322）

13) Haibo Zhang^#, Wan Chao^#, Huang Jing, Yang Chensu, Qin You, Lu Yanwei, Ma Jia, Wu Bian, Xu Shuangbing, Wu Gang, Yang Kunyu^*. In Vitro Radiobiological Advantages of Hypofractionation Compared with Conventional Fractionation: Early-Passage NSCLC Cells are Less Aggressive after Hypofractionation. Radiation Research, 2018, 190(6): 584-595（第一作者, IF=3.372）

14) Jianming Tang^#*, Guangsheng Zhong^#, Haibo Zhang^#, Bo Yu, Fangqiang Wei, Liming Luo, Yao Kang, Jianhui Wu, Jiaxiang Jiang, Yucheng Li, Shuqiang Wu, Yongshi Jia, Xiaodong Liang^*, Aihong Bi^*. LncRNA DANCR upregulates PI3K/AKT signaling through activating serine phosphorylation of RXRA. Cell Death &Disease, 2018, 9(12): 0-1167. (共同第 一 作 者, IF=9.685)

15) Yan Ma^#; Haibo Zhang^#; Cheng Chen^#; Lixin Liu^#; Ting Ding^#; You Wang; Dachang Ma; Xiaoling Ling; Xiaohua Chen; Jian Li; Guansheng; Zhong; Guoqing Ru; Lei Zhang^*; Jianming Tang^*. TRIM32 promotes radioresistance by disrupting TC45-STAT3 interaction in triple-negative breast cancer. Oncogene. 2022 Mar;41(11):1589-1599. (共同第一作者，IF=8.756)

16) Anchen Su^#, Kun Yao^#, Hanru Zhang, Yiqing Wang, Haibo Zhang^*, Jianming Tang^*. DANCR induces cisplatin resistance of triple-negative breast cancer by KLF5/ p27 signaling. American Journal of Pathology, 2023 Mar;193(3):248-258. （共同通讯, IF=6.0）

17) Shuang Li^#, Weiping Yao^#, Ruiqi Liu, Liang Gao, Yanwei Lu, Haibo Zhang^*, Xiaodong Liang^*. Long non-coding RNA LINC00152 in cancer: Roles, mechanisms, and chemotherapy and radiotherapy resistance. Frontiers in Oncology 2022;12:960193. （共同通讯作者, IF=5.738）

18) Jiayan Lian^#; Haibo Zhang^#, Fangqiang Wei^#, Qiang Li, Yanwei Lu, Bo Yu, Lili Yu, Xiaodong Liang, Yang Wen, Ketao Jin^*, Jianming Tang^*. Long non-coding RNA DANCR promotes colorectal tumor growth by binding to lysine acetyltransferase 6A. Cellular Signalling, 2020, 67. (共同第一作者，IF=4.85)

19) Xiao Wang^#, Haibo Zhang^*, Yanwei Lu^*. Breast metastasis of signet ring cell carcinoma from the colon: a case report. World Journal of Surgical Oncology. 2022 Dec 1;20(1):376.（共同通讯, IF=3.53）

20) Haibo Zhang^#, You Qin^#, Chang-Shu Ke, Jing Huang, Bian Wu, Chao Wan, Chen-Su Yang, Kun-Yu Yang^*. Primary extraskeletal myxoid chondrosarcoma in cerebellum A Case Report with Literature Review, Medicine, 2017, 96(47):e8684-e8684. （第一作者, IF=1.817）

21) Shuang Li^#, Weiping Yao^#, Ruiqi Liu, Yanwei Lu, Haibo Zhang^*, Xiaodong Liang^*. Severe lymphopenia as a prognostic factor in rectal cancer patients receiving adjuvant chemoradiotherapy: a retrospective study. Scientific Reports. 2023 May 9;13(1):7566. （共同通讯, IF=4.6）

22)  Zhang, H. ,  Wan, C. ,  Yang, C. ,  Qin, Y. ,  Huang, J. , &  Yang, K. . (2016). Stereotactic body radiation therapy gains radiobiological advantages not in non-small cell lung cancer cells after radiation but in early passage cells compared to conventional radiation therapy. International Journal of Radiation Oncology Biology Physics, 96(2), E581-E581.（第一作者, IF=7.0）

 

带教研究生6名，毕业3名，指导研究生发表SCI论文10余篇，研究生获得省级优秀毕业生、优秀规培医师等荣誉。